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sab·i·nene. ˈsabəˌnēn. plural -s. : a liquid bicyclic unsaturated terpene hydrocarbon C10H16 found especially in savin oil that is the isomer of
thujene containing a double bond outside of the rings; 4(10)-thujene.
Sabinene is a naturally occurring compound noted for a peppery and citrusy aroma. This terpene is found in cannabis but also many other plants, such as Holm oak trees, black pepper, cardamom and carrot seed.
The introduction of the one-amino acid mutation reported in a 2015 paper by Srividya, Narayanan et al. changed the limonene synthase of Ptrc-trGPPS-LS to sabinene synthase.Sabinene can be synthesized by combining this part with an upstream pathway that can supply the products of the mevalonate pathway (IPP and DMAPP).
Just as different cannabinoids have different effects, so do terpenes. These unique attributes contribute to the overall composition of a strain, adding a dimension to each one’s “personality.” Though research is still substantiating sabinene’s effects and benefits, the following uses are currently being investigated:
Currently, sabinene is used in the perfume, flavor, and pharmaceutical industries because of its pleasant odor, anti-fungal and anti-inflammatory activities, respectively.
Sabinene has been studied for its implications in soothing problematic skin conditions, relieving arthritis pain, and aiding digestion. Sabinene has been shown to possess anti-inflammatory, anti-fungal, antimicrobial, antioxidant, and antibacterial, properties.
Sabinene is responsible for the spicy, citrusy, and piney odors that make up the scent profile of some cannabis strains. We can find Sabinene in higher concentrations in haze strains of cannabis, elevating woody, citrus, and mint-like scents.
Cultivars (strains) with Sabinene Dominance
Cautions
It is important to specify normal concentrations, as some terpenes can cause irritation, allergic reaction, nausea, headache, and/or acute toxic effects at very high doses - but these doses are much higher than you would ever consume in the course of using cannabis products.
Some terpenes can be dermal irritants, so their concentration in topical products needs to be carefully controlled. Guidance from organizations such as the International Fragrance Association shows that safe limits depend both on the type of product and the individual terpene.
The pharmacological hypothesis argues that aromatic compounds such as terpenes affect mood, physiology, and behavior because they interact with the nervous and/or endocrine systems (hormones).
Sabinene is a natural bicyclic monoterpene with the molecular formula C10H16. It is isolated from the essential oils of a variety of plants including Marjoram, holm oak (Quercus ilex) and Norway spruce (Picea abies). It has a strained ring system with a cyclopentane ring fused to a cyclopropane ring.
Sabinene is one of the chemical compounds that contributes to the spiciness of black pepper and is a major constituent of carrot seed oil. It also occurs in tea tree oil at a low concentration. It is also present in the essential oil obtained from nutmeg, Laurus nobilis, and Clausena anisata.
Formula: C10H16
Molar Mass: 136.23 g/mol
PubChem CID: 18818
Density: 0.844 g/mL at 20 °C g/cm3
Boiling Point: 163 to 164 °C (325 to 327 °F; 436 to 437 K)
Flash Point: 37℃
Density: 0.858 g/mL at 25 °C(lit.)
Vapor Pressure: 87hPa at 20℃
Refractive Index: 1.4860 (estimate)
Storage Temp: 2-8°C
Water Solubility: 5.03mg/L at 20℃