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Nerolidol. noun. ne·rol·i·dol neˈrȯləˌdȯl, -räl-, -dōl plural-s : a liquid acyclic sesquiterpenoid tertiary alcohol C15H25OH that has a floral odor, that is isomeric with farnesol, and that occurs in many essential oils (as neroli oil and the oil from Peru balsam)
Nerolidol, or trans-nerolidol, is a terpene found in many strong aromatic plants such as jasmine, tea tree, and lemongrass, and it can also be found in some cannabis strains. The aroma of nerolidol is woody and reminiscent of fresh bark. It's also known for a nuanced floral aroma with notes of citrus, apples, and rose, and is often used as a fragrance or food additive.
The usage of nerolidol is widespread across different industries. It has been widely used in cosmetics (e.g., shampoos and perfumes) and in non-cosmetic products (e.g., detergents and cleansers). In fact, U.S. Food and Drug Administration (FDA) has also permitted the use of nerolidol as a food flavoring agent.
Just as different cannabinoids have different effects, so do terpenes. These unique attributes contribute to the overall composition of a strain, adding a dimension to each one’s “personality.” Though research is still substantiating nerolidol effects and benefits, the following uses are currently being investigated:
Nerolidol is known for its sedative and relaxing effects, making it a good candidate for aiding sleep. It's also known for having antioxidant, anti-inflammatory, anti-fungal, anticancer, antibacterial/antimicrobial, and anti-parasitic properties. Nerolidol can help to boost immunity, has exhibited anti-malarial, and anti-tumor possibilities, may serve as an anxiolytic, has application as an insecticidal prevention or treatment, and it enhances topical absorption.
Cultivars (strains) with Nerolidol Dominance
Cautions
It is important to specify normal concentrations, as some terpenes can cause irritation, allergic reaction, nausea, headache, and/or acute toxic effects at very high doses - but these doses are much higher than you would ever consume in the course of using cannabis products.
Some terpenes can be dermal irritants, so their concentration in topical products needs to be carefully controlled. Guidance from organizations such as the International Fragrance Association shows that safe limits depend both on the type of product and the individual terpene.
The pharmacological hypothesis argues that aromatic compounds such as terpenes affect mood, physiology, and behavior because they interact with the nervous and/or endocrine systems (hormones).
Nerolidol, also known as peruviol and penetrol , is a naturally occurring sesquiterpene alcohol. A colorless liquid, it is found in the essential oils of many types of plants and flowers. There are four isomers of nerolidol', which differ in the geometry about the internal double bonds, but most applications use such a mixture. The aroma of nerolidol is woody and reminiscent of fresh bark. It is used as a flavoring agent and in perfumery as well as in non-cosmetic products such as detergents and cleansers. Nerolidyl derivatives include nerolidyl diphosphate and the fragrance nerolidyl acetate.
Formula: C15H26O
Molar mass: 222.37 g/mol
PubChem CID:
8888 (unspecified)
5320128 (cis)
5284507 (trans)
Melting Point: -75 °C
Boiling Point: 122 °C (252 °F; 395 K) at 3 mmHg
Flash Point: 230 °F
Density: 0.872 g/cm3
2772 | NEROLIDOL (ISOMER UNSPECIFIED)
Refractive Index: n20/D 1.479(lit.)
Storage Temp: 2-8°C
Solubility: 0.014g/l
Form: Liquid
Color: Clear; slightly yellow
Water Solubility: immiscible