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History & Background:
Cannabicyclol (CBL) was first isolated in the 1960s by Korte and Sieper. It wasn’t for a few more years before its chemical structure was mapped by Gaoni, Mechoulam, and Claussen. CBL is a lesser-known cannabinoid found in the cannabis plant. It is derived from cannabichromene (CBC), which is converted into CBL when exposed to light or heat.
Properties Of CBL:
CBL is a non-intoxicating cannabinoid, meaning it does not produce the psychoactive effects commonly associated with THC. Like other cannabinoids, it interacts with the body's endocannabinoid system (ECS), specifically with the CB1 and CB2 receptors. CBL has a molecular structure similar to CBC, but with an added cyclobutene ring.
Benefits Of CBL:
Although research on CBL is limited, early studies suggest that it may have several therapeutic benefits. CBL has been shown to have anti-inflammatory properties, which could make it beneficial for those with conditions such as arthritis or inflammatory bowel disease. It also has potential as a treatment for glaucoma, as it has been found to reduce intraocular pressure. Additionally, CBL may have neuroprotective effects, which could be beneficial for those with neurological conditions such as Alzheimer's disease or multiple sclerosis. It has also been found to have antibacterial properties, which could be useful in treating infections caused by bacteria.
Risks of CBL Use:
As with other cannabinoids, the potential risks of CBL use are not yet fully understood. However, as it is a non-intoxicating cannabinoid, it is considered to be a safer option than THC. One potential concern is that CBL is derived from CBC, which is known to have anticoagulant properties. This means that individuals taking blood thinners should exercise caution when using CBL.
Cultivars (strains) With Higher-Than-Average Concentrations Of CBL:
It is derived from cannabichromene (CBC), which is converted into CBL when exposed to light or heat. Current belief is that cultivars higher in CBC stand a greater chance at retaining higher levels of CBL (more TBA).