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Eucalyptol. eu·ca·lyp·tolˌ yü-kə-ˈlip-ˌtȯl. -ˌtōl. variants or less commonly eucalyptole. : a liquid C10H18O with an odor of camphor that occurs in many essential oils (as of eucalyptus) and is used especially as an expectorant and flavoring agent. called also cineole.
Introduction:
In 1870, F. S. Cloez identified and ascribed the name "eucalyptol" to the dominant portion of Eucalyptus globulus oil. Eucalyptol is found in varying concentrations in different species of the Eucalyptus genus, with Eucalyptus globulus being one of the most abundant sources. The oil is extracted from the leaves of the tree through a process known as steam distillation.
Chemical Properties:
Eucalyptol has the molecular formula C10H18O and a molecular weight of 154.25 g/mol. It has a boiling point of 176°C (349°F) and a density of 0.92 g/cm³. Eucalyptol is known for its characteristic minty and spicy aroma, which is due to its chemical properties. It is a colorless liquid with a slightly oily consistency.
Sources:
Eucalyptol is found in varying concentrations in different species of the Eucalyptus genus, with Eucalyptus globulus being one of the most abundant sources. It is also found in other plants, such as bay leaves, tea tree, and sage.
Uses:
Eucalyptol has a variety of uses due to its medicinal and industrial properties. It is commonly used as a flavoring agent in food products, as well as a fragrance in perfumes and cosmetics. In addition, it has been found to have medicinal properties such as anti-inflammatory, analgesic, and antispasmodic effects, making it useful in the treatment of respiratory conditions such as asthma and bronchitis. Furthermore, eucalyptol has been found to have antimicrobial properties, making it effective in fighting a variety of bacteria and fungi. It is often used as a natural alternative to traditional antibiotics.
Research on eucalyptol in cannabis is still limited, but there have been some studies on its potential therapeutic benefits. One study published in the Journal of Natural Products found that eucalyptol, along with several other terpenes, had potent antifungal properties against several different strains of fungi. Another study published in the journal Planta Medica found that eucalyptol had anti-inflammatory effects in mice with induced inflammation.
Furthermore, eucalyptol is believed to enhance the effects of other cannabinoids, such as THC and CBD, by increasing their absorption through the blood-brain barrier. This is because eucalyptol has been found to increase cerebral blood flow, allowing for better delivery of cannabinoids to the brain.
Cultivars (strains) with Eucalyptol Dominance:
Cautions:
While eucalyptol is generally considered safe, it is important to use it properly and take appropriate precautions. It can cause irritation if applied to the skin in its undiluted form, and can be toxic if ingested in large quantities. Research explored, states that pregnant and breastfeeding women should avoid using eucalyptol, as there is not enough information available on its safety in these groups. Additionally, it may interact with certain medications, so it is important to consult with a healthcare professional before using it. It is also important to use eucalyptol in the proper dosage and concentration, as it can cause adverse effects if used improperly.
Eucalyptol is a monoterpenoid. A colorless liquid, it is a bicyclic ether. Eucalyptol has a fresh mint-like smell and a spicy, cooling taste. It is insoluble in water, but miscible with organic solvents. Eucalyptol makes up ~70–90% of eucalyptus oil. Eucalyptol forms crystalline adducts with hydrohalic acids, o-cresol, resorcinol, and phosphoric acid. Formation of these adducts is useful for purification.
Formula: C10H18O
Molar Mass: 154.25 g/mol
PubChem CID: 2758
Density: 0.9225 g/cm3
Melting Point: 2.9 °C (37.2 °F; 276.0 K)
Boiling Point: 176–177 °C (349–351 °F; 449–450 K)
Magnetic Susceptibility (X): −116.3×10−6 cm3/mol